Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

Kayagaki, Nobuhiko; Stowe, Irma B; Lee, Bettina L; O'Rourke, Karen; Anderson, Keith; Warming, Søren; Cuellar, Trinna; Haley, Benjamin; Roose-Girma, Merone; Phung, Qui T; Liu, Peter S; Lill, Jennie R; Li, Hong; Wu, Jiansheng; Kummerfeld, Sarah; Zhang, Juan; Lee, Wyne P; Snipas, Scott J; Salvesen, Guy S; Morris, Lucy X; Fitzgerald, Linda; Zhang, Yafei; Bertram, Edward M; Goodnow, Christopher C; Dixit, Vishva M.

Nature ; 526(7575): 666-71, 2015 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-26375259

2.

Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates.

Cuellar, Trinna L; Barnes, Dwight; Nelson, Christopher; Tanguay, Joshua; Yu, Shang-Fan; Wen, Xiaohui; Scales, Suzie J; Gesch, Julie; Davis, David; van Brabant Smith, Anja; Leake, Devin; Vandlen, Richard; Siebel, Christian W.

Nucleic Acids Res ; 43(2): 1189-203, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25550431

3.

Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi.

Watanabe, Colin; Cuellar, Trinna L; Haley, Benjamin.

RNA Biol ; 13(1): 25-33, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-26786363

4.

Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing.

Dallas, Anne; Ilves, Heini; Ge, Qing; Kumar, Pavan; Shorenstein, Joshua; Kazakov, Sergei A; Cuellar, Trinna L; McManus, Michael T; Behlke, Mark A; Johnston, Brian H.

Nucleic Acids Res ; 40(18): 9255-71, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22810205

5.

CheekAge: a next-generation buccal epigenetic aging clock associated with lifestyle and health.

Shokhirev, Maxim N; Torosin, Nicole S; Kramer, Daniel J; Johnson, Adiv A; Cuellar, Trinna L.

Geroscience ; 46(3): 3429-3443, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38441802

6.

Glycine and aging: Evidence and mechanisms.

Johnson, Adiv A; Cuellar, Trinna L.

Ageing Res Rev ; 87: 101922, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37004845

7.

Real-time quantification of antibody-short interfering RNA conjugate in serum by antigen capture reverse transcription-polymerase chain reaction.

Tan, Martha; Vernes, Jean-Michel; Chan, Joyce; Cuellar, Trinna L; Asundi, Aarati; Nelson, Christopher; Yip, Victor; Shen, Ben; Vandlen, Richard; Siebel, Christian; Meng, Y Gloria.

Anal Biochem ; 430(2): 171-8, 2012 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-22929697

8.

A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes.

Johnson, Adiv A; Torosin, Nicole S; Shokhirev, Maxim N; Cuellar, Trinna L.

iScience ; 25(11): 105304, 2022 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-36304118

9.

Human age reversal: Fact or fiction?

Johnson, Adiv A; English, Bradley W; Shokhirev, Maxim N; Sinclair, David A; Cuellar, Trinna L.

Aging Cell ; 21(8): e13664, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35778957

10.

Expanded RNA-binding activities of mammalian Argonaute 2.

Tan, Grace S; Garchow, Barry G; Liu, Xuhang; Yeung, Jennifer; Morris, John P; Cuellar, Trinna L; McManus, Michael T; Kiriakidou, Marianthi.

Nucleic Acids Res ; 37(22): 7533-45, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19808937

11.

Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration.

Cuellar, Trinna L; Davis, Tigwa H; Nelson, Peter T; Loeb, Gabriel B; Harfe, Brian D; Ullian, Erik; McManus, Michael T.

Proc Natl Acad Sci U S A ; 105(14): 5614-9, 2008 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-18385371

12.

ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses.

Herzner, Anna-Maria; Khan, Zia; Van Nostrand, Eric L; Chan, Sara; Cuellar, Trinna; Chen, Ronald; Pechuan-Jorge, Ximo; Komuves, Laszlo; Solon, Margaret; Modrusan, Zora; Haley, Benjamin; Yeo, Gene W; Behrens, Timothy W; Albert, Matthew L.

J Exp Med ; 218(9)2021 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-34297039

13.

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.

Davis, Tigwa H; Cuellar, Trinna L; Koch, Selina M; Barker, Allison J; Harfe, Brian D; McManus, Michael T; Ullian, Erik M.

J Neurosci ; 28(17): 4322-30, 2008 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-18434510

14.

ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer.

Vartanian, Steffan; Lee, James; Klijn, Christiaan; Gnad, Florian; Bagniewska, Maria; Schaefer, Gabriele; Zhang, Donglu; Tan, Jenille; Watson, Sara A; Liu, Liling; Chen, Honglin; Liang, Yuxin; Watanabe, Colin; Cuellar, Trinna; Kan, David; Hartmaier, Ryan J; Lau, Ted; Costa, Michael R; Martin, Scott E; Merchant, Mark; Haley, Benjamin; Stokoe, David.

Cancer Res ; 79(19): 4828-4839, 2019 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-31416841

15.

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC.

Dompe, Nicholas; Klijn, Christiaan; Watson, Sara A; Leng, Katherine; Port, Jenna; Cuellar, Trinna; Watanabe, Colin; Haley, Benjamin; Neve, Richard; Evangelista, Marie; Stokoe, David.

PLoS One ; 13(6): e0199264, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29912950

16.

ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.

Lee, Bettina L; Mirrashidi, Kathleen M; Stowe, Irma B; Kummerfeld, Sarah K; Watanabe, Colin; Haley, Benjamin; Cuellar, Trinna L; Reichelt, Michael; Kayagaki, Nobuhiko.

Sci Rep ; 8(1): 3788, 2018 02 28.

Artigo em Inglês | MEDLINE | ID: mdl-29491424

17.

CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing.

Callow, Marinella G; Watanabe, Colin; Wickliffe, Katherine E; Bainer, Russell; Kummerfield, Sarah; Weng, Julie; Cuellar, Trinna; Janakiraman, Vasantharajan; Chen, Honglin; Chih, Ben; Liang, Yuxin; Haley, Benjamin; Newton, Kim; Costa, Michael R.

Cell Death Dis ; 9(3): 261, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29449584

18.

Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.

Cuellar, Trinna L; Herzner, Anna-Maria; Zhang, Xiaotian; Goyal, Yogesh; Watanabe, Colin; Friedman, Brad A; Janakiraman, Vasantharajan; Durinck, Steffen; Stinson, Jeremy; Arnott, David; Cheung, Tommy K; Chaudhuri, Subhra; Modrusan, Zora; Doerr, Jonas Martin; Classon, Marie; Haley, Benjamin.

J Cell Biol ; 216(11): 3535-3549, 2017 11 06.

Artigo em Inglês | MEDLINE | ID: mdl-28887438

19.

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.

Guler, Gulfem Dilek; Tindell, Charles Albert; Pitti, Robert; Wilson, Catherine; Nichols, Katrina; KaiWai Cheung, Tommy; Kim, Hyo-Jin; Wongchenko, Matthew; Yan, Yibing; Haley, Benjamin; Cuellar, Trinna; Webster, Joshua; Alag, Navneet; Hegde, Ganapati; Jackson, Erica; Nance, Tracy Leah; Giresi, Paul Garrett; Chen, Kuan-Bei; Liu, Jinfeng; Jhunjhunwala, Suchit; Settleman, Jeff; Stephan, Jean-Philippe; Arnott, David; Classon, Marie.

Cancer Cell ; 32(2): 221-237.e13, 2017 08 14.

Artigo em Inglês | MEDLINE | ID: mdl-28781121

20.

MicroRNAs and endocrine biology.

Cuellar, Trinna L; McManus, Michael T.

J Endocrinol ; 187(3): 327-32, 2005 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-16423811

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